oisin
On the last point: https://peterjohnsen.substack.com/p/help-science-go-faster
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The parallels to early element discovery is funny—just go in a mine and find stuff, just go to a forest and find stuff.
Would you consider getting into metascience? I think it's an interesting high-leverage area you could be great in. Would probably have some people for you to chat to you if so.