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Great index for assessing the frontier drug discovery efforts along the neglectedness and impact axes, tho it is missing a metric to gauge tractability
A sad piece to have to write, but sadder still to look away
How Artificial Intelligence Shapes Science: Evidence from AlphaFold — Ryan Hill & Carolyn Stein
(carolynstein.github.io)
Interesting early evidence of complementarity, “floodlighting” & perhaps a biology-AI Amdhal’s law
Emigrating from Belfast to Los Angeles with a pit stop in Pittsburgh and San Francisco, creating the LA aqueduct, getting Mulholland Drive called after you, earning an honorary doctorate from Berkeley, and rejecting the idea of being LA mayor because you’d “rather give birth to a porcupine backwards”. What a guy!
Imagining a theme park called Fota(voltaic) Island to help galvanize the Irish towards being wholehearted stewards of technological progress, rooted in their own history of successful national STEM programs. I'm sure @oisin will have thoughts.
Great new podcast from one of the best
Finally watched Hackers. It was borderline goofy but the 90s retro somehow makes it feel more like a cultural relic than cringe. This set of interviews is cute.
Some great dystopian-realist vignettes here that I wish didn't resonate as much as they do, but I suppose they say "do not avert your gaze" for a reason.
An early vision describing humanity’s role in science as largely hermeneutical
The Rise of Partisanship and Super-Cooperators in the U.S. House of Representatives
(journals.plos.org)
Figure 2 is perhaps the most striking quantitative demonstration of growing US legislative dysfunction I’ve ever seen, and that's before taking into account everything post 2011
Interesting analysis made possible from new data sources, pointing to benefits at the metro and local level for market rate housing
My first paper as part of the Edison team!
The uncertainty threshold principle: Some fundamental limitations of optimal decision making under dynamic uncertainty
(ieeexplore.ieee.org)
My favourite reference to facetiously redirect conversations on P(doom) when I'm not in the mood to get into it all
Still on my quest for the “quintessentially Irish architectural aesthetic that delights” but in the meantime, I can’t stop loving these 18th century neo-classical gems
Repost this lynk