Progress
AI
Science
Technology
Politics
meta-science
Philosophy
History
Ethics
HCI
Essays
Ireland
Urban Planning
Blogs
design
Economics
Funny
Metrics worth Optimizing
Sustainability
Architecture
Art
Music
UX
Bayesian
Epistemology
Websites That Know Their Purpose
Dublin
Humanitarianism
Dialogue
Game Theory
Nostalgia
Public Transit
Cute Birthday Gift Ideas for Someone Special
Graphs
Maps
Maths
Movies
Pittsburgh
fonts
Lists
SF
Algorithmic Game Theory
Drug Development
Markets
Websites That Don't Need A Purpose
Language
Profile RSS
A very cute Bloomsday event in the heart of SF, with a fun history lesson about how an Irish engineer started MUNI
Foreign aid from the United States saved millions of lives each year - Our World in Data
(ourworldindata.org)
A reminder
An incredible update, perhaps the start of a flood of new genetic therapies
Interesting new tool to help innovation policymakers with a gorgeous UX
My first podcast on the wonderful new Memo to File from Luke Fehily and Tom O’Connor
Low-carbon electricity sources grew faster than demand in 2025, pushing fossil fuels into decline - Our World in Data
(ourworldindata.org)
📈
Remarks by the President on the completion of the Human Genome Project — The White House
(clintonwhitehouse3.archives.gov)
Interesting relic to reflect on in 2026
Fascinating progress on the use of in vivo gene editing therapy to protect against heart disease
🇮🇪 ☘️ 🧮
Nice natural experiment to assess the causal effect of financial assistance on homelessness.
Great index for assessing the frontier drug discovery efforts along the neglectedness and impact axes, tho it is missing a metric to gauge tractability
A sad piece to have to write, but sadder still to look away
How Artificial Intelligence Shapes Science: Evidence from AlphaFold — Ryan Hill & Carolyn Stein
(carolynstein.github.io)
Interesting early evidence of complementarity, “floodlighting” & perhaps a biology-AI Amdhal’s law
Emigrating from Belfast to Los Angeles with a pit stop in Pittsburgh and San Francisco, creating the LA aqueduct, getting Mulholland Drive called after you, earning an honorary doctorate from Berkeley, and rejecting the idea of being LA mayor because you’d “rather give birth to a porcupine backwards”. What a guy!
Imagining a theme park called Fota(voltaic) Island to help galvanize the Irish towards being wholehearted stewards of technological progress, rooted in their own history of successful national STEM programs. I'm sure @oisin will have thoughts.
Great new podcast from one of the best