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Trigger warning with this one, but I found it to be a perspective worth sharing from a person I admire.
Sometimes RCTs are hiding in plain sight
Interesting observational study suggesting most of the difference is due to larger firm familiarity with the FDA filing process, not rent-seeking or lobbying
A wonderful treat peeking behind one of my favourite Dublin record labels
🏞️🪱 → 💉♻️ → 🦠📈 → 💊💊 → 🦠📉 → 🏆🏅
An admirable application of AI
Interesting to read about in the context of AI model development in 2026
A cute collection of Georgian fanlights that shows the range of designs — also some interesting historical notes on the effects of 1700’s construction policy and the transition away from wooden window designs. Also s/o to Dublin 🇮🇪
Use of Statistics to Assess Serious Adverse Events in Clinical Trials of New Drugs: Cross-Sectional Study of FDA Review Memos | Journal of General Internal Medicine | Sarah Tanveer et al.
(link.springer.com)
Less than half of serious adverse events analyses submitted to the FDA in 2022 as part of a successful new drug application followed the statistical preferences encouraged by the FDA. Seems like the sort of problem that should not exist anymore with AI.
Some interesting “myth busting” for the 2000s Irish housing bubble
An interesting perspective in which Terrence advocates for a shift in what the field considers to be work worthy of prestige. A new emphasis is needed to aid the community curation, digestion & communication of mathematical results.
Fu n gam e t o seeho w ba d s om e f onts a re
A thoughtful reflection on trust, expanding its scope beyond the world of agential beings, featuring defensive driving and Roscoe’s chicken & waffle house.
Sanitation, human rights, aging and other invisible scaffolding of NYC life explored through artist in residency programming
A very cute Bloomsday event in the heart of SF, with a fun history lesson about how an Irish engineer started MUNI
Foreign aid from the United States saved millions of lives each year - Our World in Data
(ourworldindata.org)
A reminder
An incredible update, perhaps the start of a flood of new genetic therapies
Interesting new tool to help innovation policymakers with a gorgeous UX
Repost this lynk