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My first podcast on the wonderful new Memo to File from Luke Fehily and Tom O’Connor
Low-carbon electricity sources grew faster than demand in 2025, pushing fossil fuels into decline - Our World in Data
(ourworldindata.org)
📈
Remarks by the President on the completion of the Human Genome Project — The White House
(clintonwhitehouse3.archives.gov)
Interesting relic to reflect on in 2026
Fascinating progress on the use of in vivo gene editing therapy to protect against heart disease
🇮🇪 ☘️ 🧮
Nice natural experiment to assess the causal effect of financial assistance on homelessness.
Great index for assessing the frontier drug discovery efforts along the neglectedness and impact axes, tho it is missing a metric to gauge tractability
A sad piece to have to write, but sadder still to look away
How Artificial Intelligence Shapes Science: Evidence from AlphaFold — Ryan Hill & Carolyn Stein
(carolynstein.github.io)
Interesting early evidence of complementarity, “floodlighting” & perhaps a biology-AI Amdhal’s law
Emigrating from Belfast to Los Angeles with a pit stop in Pittsburgh and San Francisco, creating the LA aqueduct, getting Mulholland Drive called after you, earning an honorary doctorate from Berkeley, and rejecting the idea of being LA mayor because you’d “rather give birth to a porcupine backwards”. What a guy!
Imagining a theme park called Fota(voltaic) Island to help galvanize the Irish towards being wholehearted stewards of technological progress, rooted in their own history of successful national STEM programs. I'm sure @oisin will have thoughts.
Great new podcast from one of the best
Finally watched Hackers. It was borderline goofy but the 90s retro somehow makes it feel more like a cultural relic than cringe. This set of interviews is cute.
Some great dystopian-realist vignettes here that I wish didn't resonate as much as they do, but I suppose they say "do not avert your gaze" for a reason.
An early vision describing humanity’s role in science as largely hermeneutical
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